Endocrine Abstracts

Introduction: Sheehan syndrome (SS) is caused by postpartum necrosis of the pituitary gland, associated with significant haemorrhage during or after delivery. It is rare in developed countries, but still frequent in underdeveloped ones. We present a rare presentation of this syndrome.Clinical case: A 48 years old black woman presented at the emergency department for long term fatigue and dyspnea that worsened a few days before. Her physical examination r...

Introduction: Central diabetes insipidus (DI) is a frequent complication of transfenoidal surgery for Cushing’s disease (CD). It can be transient or, more infrequently, permanent. The most common mechanism results from surgical neurohypophyseal damage rather than local mass effect from the pituitary adenoma.Case report: A 40 years old woman was referred to our Endocrinology outpatient clinic at the beginning of 2015 for new onset hypertension, signi...

Although primary hyperparathyroidism (PHPT) is usually cured by surgery, some individuals are unable to undergo parathyroidectomy and are refractory to standard calcium lowering medical therapy. In such cases, targeted therapy with cinacalcet may be useful.The aim of this study was to access the short-term efficacy of cinacalcet in lowering calcium (Ca2+) levels in patients with PHPT unable to undergo parathyroidectomy and refractory to standa...

Introduction: Gestational Diabetes Mellitus (GDM) is one of the pregnancy diseases with the highest rate of complications, influenced by several factors. Its prevalence has increased, with a prevalence of 7.2% in Portugal.Objective: Characterize pregnant women with GDM and evaluate the perinatal outcomes according to the country of origin and previous GDM.Material and methods: Cross-sectional and retrospective study. We collected c...

Introduction: Amiodarone is an antiarrhythmic iodine-rich drug, known to induce thyroid dysfunction both due to its high iodine content and through amiodarone-induced thyrotoxicosis (AIT), being this latter process classified into three different types. Type 1 is associated with increased thyroid hormone synthesis; type 2 is a destructive process with thyroid hormone release and type 3 is thought to be a mixture of the former two. Since treatment options are different, there h...

Paediatric Graves’ disease (PGD) is an uncommon autoimmune disorder with a multifactorial origin. Although, in some autoimmune endocrinophaties the seasonality of month of birth (MOB) distribution differed from the general population, this association has not been study in PGD. The aim of this work was to analyse the impact of seasonality of MOB on PGD incidence in Portugal.In 2013, the Portuguese Paediatric Society of Diabetes and Endocrinology und...

Thyroid storm (TS) is one extreme of a continuum beginning with thyrotoxicosis. It’s rarely caused by exogenous thyroid hormone intake (ETHI). Aggressive medical therapy is the cornerstone of treatment; nevertheless, it might not be sufficient. Plasmapheresis is an extracorporeal technique that can rapidly lower thyroid hormone levels. The aim of this study was to assess the efficacy of plasmapheresis in TS secondary to ETHI. We evaluated retrospectively all TS cases (Bur...

Introduction: Pheochromocytomas (PHEO) and paragangliomas (PGL) are rare catecholamine-secreting tumors. Some authors proposed that there is a positive linear relationship between tumor size and measurements of metanephrines and an absence of association with catecholamine levels.Objectives: To review and characterize patients diagnosed with PHEO and PGL in Garcia de Orta Hospital. To determine the relationship between tumor size and measurements of urin...

IntroductionDue to the COVID pandemic, Portugal was forced to start lockdown on March 18 th that lasted until June 1st. Lockdown caused a lot of changes in the daily activities of the Portuguese people, such as eating habits, exercise, time spent at home and stress management. After the lockdown people noticed difficult access to healthcare.ObjectiveOur aim was to evaluate if these changes had an i...